An example of an observation would be walking into your house after a long day and smelling gas and seeing signs of smoke coming from the kitchen. From this you can infer that something is on fire in the kitchen and is burning up.
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This article discusses the use of whole genome sequencing to help asses and improve the speed of genomic diagnostics for critically ill newborns, with the hope of reducing any long, in-conclusive testing for the clinical care needed for the child. The research took place at the University Medical Center Groningen, Netherlands.
Gene diagnostics is a very time-consuming process, and not all symptoms or features of genetic syndromes are present at a child’s birth, so to limit the rate of suffering, disease, and death, whole genome sequencing was introduced as possible solution. The sequence simultaneously tests for the presence of mutations for all known gene diseases and chromosomal variants. With the rapid genomic testing, results can be concluded in a span of 12 days compared to 6 months. As a result of this, researchers were able to diagnosis 30% of the critically ill newborns. As testing grows more popular, researchers will add more of a variety of patients in their study, analyzing their full genomes.
When I first discovered this article, I did not know what to expect when reading the title. I did not know of the egg based vaccine growth process so that was my first spark of interest, but then with further reading learning about the setbacks of the process also drew me in. I find this predicament to be relatable to the problem of antibiotic resistance, bacteria are becoming resistant and gaining advantageous adaptions in order to survive and beat its competitors. The virus in the same way are gaining mutations due to its exposure, advancing so they can survive longer in certain environment. It is the job of scientists and future scientists to find ways to combat these problems and find other suitable alternatives and reliable sources in keep the human population healthy.
In a recent discovery, the process of growing the components of an influenza vaccine in chicken eggs disrupts the major antibody target site on the surface of the virus, thus causing the vaccine to be less effective in humans. The vaccine is injected into the eggs, allowing for replication and then purification of the fluids to extract the virus. However, as the prevalence of the H3N2 virus increases, only 33% of flu vaccines are effective against it. When H3N2 is grown in eggs a specific mutation named LI94P disrupts the region on the protein that is usually recognized by the immune system. Because of this, a vaccine with the mutated protein cannot generate an efficient immune response. Researchers are still further studying the virus and its response, they are also hoping for a substitute in egg base vaccine inoculation.
What did I do today you ask. Well what I did today goes as followed; I woke up late around 10:30am because I was up all night not really feeling to well, luckily I made it to the class that I am actually enrolled in around noon time. I try to attend a chemistry course that I am not yet enrolled in because I want to get an understanding if I will like the professor and thier teaching style, but however I did not make it to that class this week, hopefully by the end of the add/drop period I can secure a spot. The class usually meets at 11:15 so it fits perfectly into my schedule. I attended my microbiology class it is an average course however, the professor runs through the slides fairly quickly so it's hard to take hand written notes in class. I mostly just take notes on my laptop and then transcribe them into my notebook after during my free time. I am hoping to go to their office hours soon to get more extra help so she can explain what is going on in class. I am fairly hungry and tired at this point in time during the day I would love to eat and or sleep but I sadly I cannot. Frankly my day is dull, due to all the walking back and forth from classes or meetings and the snow and cold weather hardly help.
Both articles seem to contain level 1 headings for the main title of each article (centered and bold-faced) however, the sub-titles for each section of the articles contain level 2 headings that are left-aligned and bold-faced. Each section of the articles are structured in steps, such as the steps and processes the scientists took to develop and conduct their experiments. It breaks down the processes of the experiment so it is much easier to read, understand, and analyze. Each section identifies what part of the experiment has been conducted and gives a detailed analysis of what occurred or what results were recorded. The first paragraph of each section gives a small intro into what the section will discuss a little background knowledge and a transition from one paragraph to another. It appears that the paragraphs in both articles contain a logical flow of ideas as the ideas are organized in almost a chronological order of occurrence during the experiment. However, I would say that the first article has better flow of topic sentences, while the second article is more chopped and could be read in sections without going through the entire article.
I see tree bark samplings that resemble wood chips, there also appears to be a creature moving in this tiny plate, possibly eating the wood chips. It is moving about in a circular direction because of the limited space provided. It has a long end or tail, needle thin-like, it reminds me of a worm or millipede or centipede but shorter in its body structure. It is trying to climb out the bowl but the surface is too slippery for the creature to grasp and have a firm holding of the surface to exit. At first, I thought this creature was a plant until it started to move and it frightened me. It has transparent skin and fur or a fuzzy like texture on its body, probably for sensing what is in its environment and also a possible use for transportation and movement. At this moment, I do not believe the creature or insect is eating the woodchips, I think it is more of a comfort factor for the type of environment it dwells in. This creature is clearly an invertebrate by the way it travels in the dish. There are also no visible facial features such as eyes, nose, ears etc. I believe most of its body is sensory embowed.