The conclusions of this study include the nucleus accumbens’ ability to have its dopamine-producing neurons release dopamine and glutamate at the same time into synapses. This can mean that the nucleus accumbens has an increased ability when responding to stimuli that are significantly driven and motivated. Dopamine neurons being able to release glutamate along with dopamine can mean that they express something similar to a VGLUT2 that allows glutamate to be packaged into synaptic and secretory vesicles. This shows that glutamate does not need the light-stimulation release of dopamine. Glutamate just gets released by dopamine neurons themselves. Despite this happening in the nucleus accumbens, it is not the same for the dorsal striatum. This shows that VGLUT2 is still needed for glutamate to be gathered into synaptic vesicles in order to be released into synaptic terminals containing dopamine. As of now, the nucleus accumbens is the only exception because it does not need VGLUT2 to release glutamate. The conclusions for the most part follow logically from the design and results. Just because VGLUT2 is not needed in the nucleus accumbens does not mean dopamine itself can release glutamate with it. There could be a different factor besides the VGLUT2 and the dopamine that could be causing the glutamate release.
Comments
Comment
Im sure the other paragraphs of this paper explain more but I think including a little bit more descriptive overview at the begining would make the paragraph easier to read. It seems like right now there are many different topics that dont perfectly line up with eachother.
Wording
Instead of saying "for the most part", it would sound better to either identify what doesn't follow logically, or to omit it all together and just say "The conclusions follow logically..."