Physiology homework on acetylcholine inhibitors

Acetylcholine(ACh) is a neurotransmitter that is predominantly located amongst the peripheral nervous system but is also found in the central nervous system. Acetylcholinesterase(AChE) is an enzyme that removes excess acetylcholine from the synapse. The removal of the enzyme will cause a buildup of ACh, and in return, this causes overstimulation of glandular cells, autonomic ganglia, glial cells, the central nervous system, skeletal muscle, and smooth muscle. The two types of cholinergic neuron receptors nicotinic and muscarinic will both be affected differently. The nicotinic receptor controls a sodium and potassium ion channel the increased concentration of ACh will cause the channel to remain open. The muscarinic receptor controls the release of G proteins which can do a number of things in a cell-like open or close an ion channel, and activate or deactivate an enzyme.