Glycosylation is the covalent addition of sugar groups to specific amino acids on petide bond chains. This process of sugar addition has lasting effects on the proteins location, shape, function and stability. In recent studies researchers have found that the glycosylation of immune receptors results in increased activity of both programmed cell death factors and anti-tumor factors as well. This specific study focused on the effects of the glycosylation on Triple-Negative breast cancer cells. The study also showed that the glycosylation process can also have inheritant effects on neighboring cell. This exciting revelation means that pairing immune checkpoint therapy with protein glycosylation could prove to be a very effective beneficial treatment for cancer, specifically Triple-Negative breast cancer.
Recent comments