Bv8 is also known as Prok2 which stands for Prokineticin 2 and is known to be expressed in bone marrow. Bv8 is expressed in Cd11b+Gr1+ cells and it controls mobilization of these cells from the bone marrow during the formation of tumors. Bv8 is also involved in promoting angiogenesis . The Prok2 signaling pathway is involved in regulating a diverse set of biological process through a variety of intracellular signaling pathways like calcium mobilization
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