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Organophosphate antidote

Submitted by ameserole on Wed, 03/28/2018 - 14:14

Atropine would enter the synaptic cleft and bind to the receptors that usually bind to ACh. This means the atropine is acting as a competitive inhibitor. This function can work as an antidote because instead of ACh continuously binding to the receptors unable to be removed from circulation, atropine would bind to some of the receptors, making ACh unable to bind. When atropine is bound to the receptor it doesn’t elicit a response so the unwanted response is unable to be triggered by the ACh.

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