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Malathion

Submitted by ameserole on Tue, 03/27/2018 - 21:23

If an organism was poisoned with malathion, there would be major malfunction in the cholinergic neurons. Acetylcholine, a neurotransmitter that is used both in the PNS and the CNS would be released from the neurons, and acetylcholinesterase would be taken out of the normal cycle where it breaks ACh down into its substituents. There would be an overabundance of acetylcholine binding to receptors, as it would continue to be released from nerve cells, and would never be removed from the synaptic cleft by acetylcholinesterase. This would cause a greater response and a continued response from the receptors, something that the nerve cell wasn’t intending.

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