Chromosome mis-segregation can lead to a number of physiological issues both in the short and long-term and its effects are still not fully understood. Despite being shown to cause decreased cellular proliferation, aneuploidy is seen in an astounding 90% of solid tumors and 50% of blood cancers. Continued research is needed, however studies have shown that aneuploidy and CIN can both promote and inhibit tumorigenesis. A greater understanding of the role aneuploidy plays in tumorigenesis could shed light on the possible development of new cancer therapies in the future.
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