In 2001, the Nobel Prize in Physiology or Medicine was given to Leland Hartwell, Timothy Hunt and Paul Nurse for their discoveries of the key regulators of the cell cycle. This literature is the lecture given by Leland Hartwell on his Nobel Prize winning research as well as decades of research by a multitude of different scientists that led to the understanding of the cell cycle. In the lecture, Hartwell discusses the discovery of several important players in the cell cycle as well as their role, the effects of cell cycle mis-regulation, and the possible medical applications involving cancer treatment.
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