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Submitted by fmillanaj on Thu, 11/08/2018 - 17:46

A-site: the ribosomal site most frequently occupied by aminoacyl-tRNA. The aminoacyl-tRNA in the A-site functions as the acceptor for the growing protein during peptide bond formation.P-site: the ribosomal site most frequently occupied by peptidyl-tRNA, i.e. the tRNA carrying the growing peptide chain. The P-site is also referred to as the puromycin-sensitive site. Puromycin is an antibiotic which shows similarities with a part of aminoacyl-tRNA. When puromycin is present in the A-site, the peptide can be linked to puromycin via a peptide bond. Thus, peptidyl-tRNA in the P-site is located in the puromycin-sensitive site. E-site: the ribosomal site harboring deacylated tRNA on transit out from the ribosome.

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This paragraph seems like it was a part of something larger and it opens and closes abruptly. However, what there is relatively clear and with the addition of some background I believe this could be a really good paragraph. 

jmalloldiaz

Thu, 11/29/2018 - 20:25

This paragraph could be rewritten to have more flow. For example, starting sentences like "The A-site is the most frequently occupied ribosomal site..."