Promethease Report (3)

SNPs that are “not set” have no distinct “good” or “bad” repute. One of these identified in the Promethease report is rs11803731(A;A), a  SNP on the Trichohyalin (TCHH) gene which is associated with hair curliness. A study of Australians of European ancestry determined that the TCHH gene accounts for an estimated 6% of the hair morphology variance. The genotype that is homozygous for the “T” allele is associated with curlier hair, whereas the homozygous “A” genotype is associated with straighter hair. One of the popular SNPs identified on SNPedia is a SNP in the oxytocin receptor which influences social behavior and personality. The rs53576 SNP in this individual was identified as having the A/G variation, which is classified as “bad” because the G to A change in the “good” G/G genotype is associated with a potential lack of empathy. According to studies, individuals with the G allele are more sensitive and empathetic than those with even a single A allele, and may even handle stress better.