Obesity is not only a problem within itself but I can cause more problems later on such as type 2 diabetes, heart disease and more. Knowing that a single disease can lead to may other diseases sparked my interest as there may be a solution. Ghrelin is a peptide hormone that increases a person's hunger and causes the pituitary gland to secrete a growth hormone. Blocking the receptor for ghrelin would not be a wise choice because it could also cause changes in behavior and mood. Scientists then thought about blocking the pathway of ghrelin, which led them to find the molecule YIL781. YIL781 is specifically a molecule that is released by ghrelin that causes the feeling of hunger. So ghrelin can change the intensity or probability of behaviors. Therefore, the number of ghrelin being released and binding to the receptors changes throughout the day as the person eats and doesn't eat. Ghrelin would have different intensities depending on the time of day.
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