Promethease Report (1)

Of the SNPs analyzed in the Promethease report, 55.94% were good, 0.97% were bad, and 43.09% were not set. Of the good SNPs, one identified was rs7294919, which shows a fairly strong link to a reduced volume of the hippocampus. The hippocampus is a structure in the brain that is critically involved in learning and memory, particularly associated with the ability to form long-term memories. It shrinks with age, and its size is diminished in disorders such as Alzheimer’s. The decrease in hippocampal size is associated with the T allele, each copy of which is associated with a 107.8 mm3 decrease, while the C allele has a connection to a moderate increase in hippocampal volume. This individual has the C/T variation, which means that there is a less reduced hippocampal volume.