Metabolic couping between biochemical pathways is an essential mechanism that concentrates on the transfer of energy that is released from an exergonic pathway to provide energy needed for an endergonic pathway. Metabolic coupling occurs in a series of connected reactions; in which these reactions share products/substrates. A main method of energy transfer in these biochemical processes is the removal of phosphate groups by hydrolysis. Molecules with more negative delta G of hydrolysis can phosphorylate molecules with less delta G of hydrolysis. The energy that is released by hydrolysis is used to power other reactions. ATP is known as the main energy currency molecule. The intermediate delta G of hydrolysis of ATP to ADP + Pi releases enough energy to be useful for other biochemical pathways/reactions. The formation of ATP from ADP + Pi would be a dehydration reaction and does not require an excessive amount of energy.
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