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Karyotyping Perfect Paragraph

Submitted by kwarny on Fri, 03/29/2019 - 14:13

Karyotyping is a representation of chromosomes captured at metaphase during meiosis or mitosis. When the chromosomes reach the metaphase phase, the division is halted and then the chromosomes are arranged by size into a karyotype. Several kinds of banding exists including, G-banding, Q-banding, C-banding, and R-banding. G-banding dyes heterochromatin in the chromosomes, Q-banding finds areas rich in A-T vs. G-T and dyes them to identify the homologous chromosomes. C-banding dyes centromeric heterochromatin and R-banding is the reverse of G-banding . With today’s modern technology, softwares can analyze the banding types once it is dyed and arrange them. Moreover, DNA in the nucleus are found in two forms, heterochromatin and euchromatin. Heterochromatin is tightly packed DNA material, whereas euchromatin is loosely packed chromosomes that become active during transcription. Many of these features can be visible with karyotyping method.

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You could maybe mention how heterochromatin and euchromatin are identifiable on a karyotype, and also specify how division is halted during metaphase

You should mention how the chromosomes are "frozen" in metaphase. It leads to many questions as how it could be done.

"the metaphase phase"

-I would reccomend rewording this just so that "phrase" is not repetitive