Irisin and Alzheimer’s Prevention

Exercise assists in maintaining the health of a person. New studies have found that exercise can also assist the brain in resisting Alzheimer’s disease. Mice were used in the study to see whether irisin had a role in increasing brain function. Mice with dementia were injected with the irisin protein and was found to do better on memory tests. Irisin is created through the cleavage of FNDC5 protein. FNDC5 increases through exercising, when you exercise more it would cause more FNDC5 to be cleaved and more irisin secretion. Irisin works by causing a change in gene expression of the beta amyloid.