Enzymes are relatively complex. They can function in many different ways. There are many enzymes however they are almost all meant to interact with just one substrate. The main point to enzymes is that they lower activation energy of a reaction, whether or not that reaction is exergonic or endergonic. Enzymes only affect the free energy of the transition state, this means that enzymes only have the ability to lower the activation energy of a specific reaction in which they can bind to that substrate. Enzymes don’t affect the free energy of either the products or the reactants, this is what makes them so complicated. It only affects the energy it takes to get the reactants to the product stage. The start and end state of the reaction will always be the same regardless of an enzyme being present. Additionally enzymes don’t affect the concentration of products or reactants. What this means is that the concentration of products and reactants will always be the same no matter if there is an enzyme present in the reaction. What all of this information means is that enzymes can’t affect the favorability of a reaction, it can’t make it more or less favorable, it can only speed up the reaction in order to get all reactants to be products.
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