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Submitted by jnduggan on Wed, 11/14/2018 - 01:19

Crispr/Cas9 has come into the spotlight due to recent research, where it has been found to be a possible new tool in genome editing. The possibilities are endless in what can be done with controlled genome editing but to begin the journey on deeming it a successful option further research on humans must occur.

     The Crispr/Cas9 mechanism essential is comprised of two parts. The regulatory part of the system is a RNA guide which is programmed to sequence to match a desired DNA sequence. The RNA guide is then bound to Cas9, a protein that has the ability to make double stranded DNA breaks. When the two are together, they essentially search through the DNA looking for the programmed sequence, and once the RNA binds to the DNA, Cas9 can make the cut. The cut in DNA allows for the ability to correct mutation, insert new genes, or remove certain genes from the human genome.

 

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