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Parental Influence on Genome
- Embryos that have only one of the two sets of parental chromosomes = uniparental embryos
- Process to give embryos specific chromosomes from one parent only = uniparental disomy
- Is this done to just investigate specific chromosomes? Or, are there natural processes where certain chromosomes from a set get transferred and others don't? (seems unlikely)
- Previous research has shown that mammalian genes can function differently dependent upon whether they come from mother or father.
- Imprinted genes are expressed differently on paternal and maternal genes (first discovered, 1990s)
- Methylation marks imprinted genes differently in egg and sperm
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