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pp metabolic coupling

Submitted by msalvucci on Mon, 11/26/2018 - 14:21

Metabolic coupling is the process of using energy that is released from an exergonic pathway to provide energy needed for an endergonic pathway. The main goal of metabolic coupling is to end with a negative change in free energy (delta G). A negative change in free energy indicates a spontaneous reaction. Metabolic coupling can exist in three forms: between biochemical pathways, within biochemical pathways and within chemical reactions. Energy transfer within metabolic pathways involves the removal of phosphate groups through hydrolysis, thus resulting in a large negative free energy value. The amount of free energy available in the bond is called the phosphoryl group transfer potential. Phosphorylation is the reverse reaction of adding phosphate groups through the input of energy (ATP).



The paragraph is very well worded and written for an audience with experience in that field.  It is formatted well and sounds great, but to an acvergae person they cannot understand this as only complicated terms are used.


You did a good job describing the process of metabolic coupling and what you have is well written. However, I would try to add a sentence to close of the paragraph.