Like eukaryotic DNA, prokaryotic DNA (plasmids) must segregate during replication. This idea is interesting because of the structural differences between eukaryotic DNA and plasmids. Plasmids are essentially circular pieces of DNA the attach at both ends. A plasmid is generally condensed, similar to how a rubber band twists up. The potential energy stored in the condensed plasmid configuration can be used to propagate certain interactions. Since our eukaryotic cells utilize microtubules in chromosomal segregation, I wonder how microtubules interact with plasmids; their structure is different, so I imagine their segregation is similarly different when compared to eukaryotic DNA.