The central dogma of microbiology is the idea that there is movement of information from our genome to a movable RNA strand, and then it is translated into a protein. In relation to cancer, this process is extremely important because the function of the protein can be traced back to the coding of the DNA. Any issues with said protein could help identify how cancer cells pass down cancerous behavior, how such a behavior is transcribed, and what happens when this protein tries to function. The mutation in a genome can elicit a mutation in a proto-oncogene (pushy positive proteins in healthy cells) and tumor suppressors and thus a tumor is now able to form. When a proto-oncogene is mutated it becomes an oncogene and always remains active, signaling to the cell to continuously grow and develop without stopping.
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