interesting thing about science
in the article and the data set that was studied in class so far, the data indicated that in patients with FH, they have a receptor lacking which allows them to take up LDL, which contains cholesterol into their bodies. This is partically because they have a mutation that prevents them from having a functional receptor. On the other hand of the spectrum are patients who do not produce LDL that can be absorbed into the body. Because these two mutations both end up having the same effects, namely neither one of them is able to get into the cell, the body reacts in similar ways, with patients that have FH and malfunctioning LDL both having a higher amount of cholesterol in the blood compared to a normal person. Because of the high cholesterol, these people are also more likely to get heart diseases and are at risk for cardiac arrest. However, the degree to which the person suffers differ depending on which mutation type that person has. If the person has a malfunctioning LDL, they are more likely to have heart disease and high cholesterol, but they are noticeably less severe compared to people who have an FH mutation. People who have this mutation, especially those that are homozygote for it is very likely to have cardiac arrests in their 40s if they are het and in their teenage years if they are mut for the gene. It is interesting to note that even though the mutation does have similar effects, the overall effect on the entire system is completely different. Trying to determine the cause of why such a thing happens is both a scientific and logical feat in which the research will need to be explained and the reason why such a result will mean that the evidence supports one side of the proposed reason over another one. Personally, I think that this is one of the most difficult things in doing research. the techniques are relatively easy once a person gets used to it, but trying to prove something to be true through logic is still difficult. For example, darwins theory of evolution is logical to the point that if all facts were removed from it it would all make sense. All it needs to be done now is to just prove the basis of the logic to be correct, and the theory has to be correct.
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