The nuclear envelope in eukaryotic cells has an extremely important job: organizing and protecting the genetic material of a cell while allowing it to be manipulated as needed to allow for proper life sustaining functions. Most people learn about the nucleus of a cell in their first basic biology course in middle school, yet the actual functions of the nucleus are often obscured and simplified beyond the truth. The nuclear membrane consists of thousands of proteins embedded in the lipid bilayer that act as pores for enzymes, transcription factors, and other signaling molecules to pass through. The nuclear envelope itself has a significant involvedment in the cellular cytoskeleton as the location and movement of the nucleus is highly regulated. Nuclear lamina are the intermediate filaments proteins around the nuclear membrane. The lamina has two types of proteins that do not co-localize. Type A is associated with the nuclear pore protein complexes specifically and type B is restricted to the organizing fibers, and is constitutivly expressed and can always be detected in nuclei (Xie).
Xie W, Burke B. Nuclear networking. Nucleus. 2017;8(4):323–330. doi:10.1080/19491034.2017.1296616
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