The basic aim of the paper is to analyze the effect of thyroid level on OPCs marker and MVP level in SVZ, olfactory bulb, and optic nerve. The way that this was done is by increasing or decreasing the thyroid hormone by giving PTU or T3 thyroid hormones. The result of the study is that hyperthyroidism caused a decrease in MBP and a decrease in differentiation while hyperthyroidism caused an increase in MBP and an increase in the maturation of oligodendrocyte. From this result, the most reasonable way to infer how the result of this study can help me infer how the T3 and T4 hormones affect the neural stem cell is that there is an increase when there is a decrease in thyroid level, and a decrease when the thyroid level increases. The reason why I think this is because when the neural stem cells divide, they divide into two, and then one of the resulting cells would differentiate unevenly leaving one of the cells unusable and the other one would not be a stem cell Because of this, there would be an increase in neural stem cell because the decrease in the thyroid hormones I think would stop the division at when the neural stem cells are dividing evenly and as a result, there would be an increase in the stem cells. The increase of thyroid hormone would cause the cells to split unevenly and as a result, there would be fewer neural stem cells.
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