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Perfect Paragraph 11

Submitted by dfmiller on Fri, 12/06/2019 - 13:47

In the developing tooth, enamel deposition varies among organisms. In omnivorous homo sapiens, enamel strength and quantity is much less than that of a sea otter, who prodominantly feeds on hard shellfish. It is important, then, to understand this pathway that results in this differential deposition of enamel in developing teeth. Stem cells in the developing teeth that express Sox2 travel to the inner enamel epithelium within the developing tooth1. There, they give rise to transit amplifying (TA) cells that rapidly divide, move to the distal tip of the developing tooth, and differentiate into ameloblasts1. Ameloblasts deposit enamel matrix proteins. As a result, Sox2 overexpression could lead to increased enamel deposition and a hardening of teeth.

(1) Li, J., Parada, C., & Chai, Y. (2017). Cellular and molecular mechanisms of tooth root development. Development, 144(3), 374–384. doi: 10.1242/dev.137216



In the first sentence, "In tooth development". Homo sapien is a scientific work and should be italisized. 

While your use of the "TA" acronym is not wrong, it is unnecessary because you do not refer to "TA" cells later in the paragraph.