The overall objective of our proposal was to identify subjects that contain a highly conserved gene that can be characterized by the amount of expression. One specific aim the proposal had was to identify highly conserved genes that are present in the Animalia kingdom. In the development of animals, there is a period of embryonic similarity, where both the appearance of the embryos and the expression of their genes are conserved. The existence of this period is associated with the appearance in the evolution of stable building plans. In HOXC genes, the genes themselves are located in a specific order on chromosomes. Therefore, a consistent pattern of activation of HOXC genes is necessary in order for the body to form correctly. However, the mechanism and regulation of the HOXC genes themselves remain unclear.
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