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Submitted by smomalley on Thu, 09/26/2019 - 22:12

In-situ hybridization is a method used in many different areas of science. This is a lab technique where anti-sense mRNA probes are used to target spacific mRNA sequences in an organism. This method allows scientists to locate cells where specific genes are expressed. The mRNA sequence is targeted for a reason. Every cell in the body has the same DNA sequence, so targeting a section of DNA would label every cell. Proteins are made as a result of the central dogma; proteins are exported from the cell to other cells, so it is not possible to determine the specific cells that encode for that gene. This method allows you to pinpoint the exact cells that encode a specific gene, and count those cells. This process is very useful in genetics and neuroscience in particular. This method can be used in any area of the body and with any organism, so you can compare where one gene is expressed in different organisms.