For my Advanced Genetics class, I had to read an article and respond to it. This is my response below.
After reading this article I found it interesting that CRISPR is already being used for experiments like this one. It did not surprise me that removing transcriptional factors also hindered the expression of certain genes. However, I was surprised that this retrovirus spanned multiple mammalian lineages. This is another branch in the evolutionary tree that links us closer to other species. One question I have about this article is, if these endogenous retroviruses started out as virus, isn't there a chance that the virus used reverse transcriptase to incorporate itself into our genome?
Chuong EB. Elde NC. Feschotte C. Regulatory evolution of innate immunity through co-option of endogenous retroviruses. Science. <http://science.sciencemag.org.silk.library.umass.edu/content/351/6277/10.... Accessed 2017 Mar 3.