Bacteriocins are peptide chains that are produced by bacteria that are lethal to other bacterial strains. They are an attractive replacement for traditional antibiotics for many reasons one of which is there potential for coevolution with bacterial strains. As they are produced by bacteria bacteriocins they benefit from the same rapid evolution as the genes for antibiotic resistance. This means they have the potential to counter the evolution of bacterial resistance by evolving themselves to get around the mechanisms of resistance. To compound this bacteriocin resistance in bacteria is rare with only a few known genes having arisen to confer resistance. Bacteriocins also have a very low toxicity, they are even given the GRAS ( generally recognised as safe) status. In addition to this bacteriocins are often narrow spectrum, meaning they affect only a small number of closely related bacterial species. This mean that bacteriocins would lack the digestive side effects associated with traditional antibiotics, as they would not affect the probiotic bacteria of the human microbiome that are associated with digestion. Bacteriocins have also been found to be produced by a number of probiotic bacteria including Fusobacterium mortiferum.It has been demonstrated that these probiotic bacteria of releasing bacteriocins in situ, meaning that they release the bacteriocin while in the intestines of humans and other mammals. Such bacteriocin release in situ has been shown to prevent and treat infection in experiments using mice as a model organism. In conjuncture all these traits give bacteriocins the potential to be the antibiotic of the future and make them one of the most attractive areas of medical study.
You are here
Each week, post your own Perfect Paragraph and comment on three Perfect Paragraphs. Suggest improvements. Don't just say "Looks good."
- Try to be much more precise 6 hours 1 min ago
- great paragraph! i would 6 hours 2 min ago
- Comment 12 hours 6 min ago
- Comment 12 hours 9 min ago
- Comment 12 hours 11 min ago
- Ethics Comment 1 day 1 hour ago
- PP comment 1 day 1 hour ago
- Perfect Paragraph: Zebra fish Lab 1 day 1 hour ago
- Good paragraph on action 1 day 3 hours ago
- This is informative and 1 day 3 hours ago