Week 08: Research Proposal Appointments; Writing for Persuasion

Submitted by sbrewer on Sun, 03/19/2017 - 14:38

Meeting Location

BCRC (M311S)


We will conduct an activity this week about writing for persuasion.

Much of the rest of class this week will be devoted to a working-session where groups can meet to work on their Research Proposals, although if other times work better for your group, attendance is not required during the class period.

Earlier in the week, however, I would like each group to arrange to meet with me one-on-one (or is that three-on-one?) for a half-hour period to discuss your research proposal.  If no earlier time can be found, we can use part of the class period for these appoitments. When you come, bring your research question and literature review for us to evaluate and work on together.

Several groups have already set a time. To schedule a time, identify one or two times that will work for your group and email Dr. Brewer. Thursday is still pretty open and, of course, Friday morning (although other times may also be possible). If you can find no other time, indicate that you will meet during class time.

Required Activities

  1. Schedule a time for your group to meet one-on-one with Dr. Brewer to discuss your Research Proposal
  2. Before meeting:
    • Develop your Research Question
    • Develop a bibliography that should include:
      1. The most recent relevant review paper (or papers)
      2. One or more research papers that use methods like the ones you propose for your project
      3. Key historical papers that support your topic (identified using review papers)


Submitted by jiadam on Fri, 03/24/2017 - 15:53

Abl kinase

A normal abl kinase works with different signal adaptors kinases, phosphatases and cell regulators. They work in many cellular processes that control cell growth/ division as well as operate in the cell survival pathway. In addition, the abl kinase is active in oxidative stress, DNA damage repair, actin, and cell migration. Because of its overreaching ability, it is strictly regulated and this partly thorough localization. It is also regulated through intramolecular interactions and phosphorylation. This is important because if the process was not tightly regulated we would see a lot more bcr-abl translocation events. The kinase contains a nuclear import signal and nuclear export signal so that it can travel to and fro the nucleus. When abl is active in the nucleus, it signals through the DNA damage response pathways. In the cytoplasm it deals with actin dynamics and cell migration. If abl was not able to travel to the nucleus, it loses its ability to work in DNA damage response pathways.

Saving Labrador Retrivers Persuasive

Submitted by eriklee on Fri, 03/24/2017 - 15:21

The dog breed to save with the retrovirus vaccine are labrador retrievers. They have large litter size and long lives. They provide several services for humans, such as therapy, hunting, guiding. More importantly, labradors have great temperament and personality. They are very friendly to adults, kids, and strangers. Their personalities consist of loyalty, compassion, intelligence.

Dog Breeds

Submitted by kcapri on Fri, 03/24/2017 - 15:07

There are over 300 different breeds of dogs. Many of them are very closely related because their genetic code is rather simple and can be easily adapted with drastic changes as a result. For example, type of hair or ears is controlled by only a single gene.

If there was only one breed of dog chosen to be saved, I believe it should be the Labrador retriever for a couple of reasons. For one, they are energetic and easily trained, which could be a great way to adapt them to different service dogs that we need in our society, such as dogs for the disable and also for the police force. Additionally, they have a large liter size, which can help replenish the dog population faster. Though, I wish I could save them all.





in class persuation argumnet

Submitted by jdantonio on Fri, 03/24/2017 - 15:06

If only one breed of dog could be saved from this retrovirus then our group (group 5) proposes that we save the alaskan malamute. The alaskan malamute is among the oldest breeds of dogs being among the 16 basal dog breeds and thus has the potential to allow for the recovery of modern breeds from the more ancient lineages. The alaskan malamute is also very hardy being bred for endurance and stamina.  They are trainable dogs that are capable of being used as sled dogs. Malamutes are highly affectionate towards humans being protective and make great family pets.

Dog persuasion exercise

Submitted by koganezova on Fri, 03/24/2017 - 15:04

We were presented with a scenario that went: A new retrovirus is killing domestic dogs at terrible speed, in a few months all domestic dogs are predicted to be extinct. However, scientists have developed enough vaccine to save one pregnant mother and her puppies: which breed dog should be saved?

My group and I concluded that the breed of dog that should be saved should be a member of the oldest breeds of dogs. One breed includes the husky, which has been around since the 19th century. We thought this because since they are one of the original breeds of dogs and have not been heavily selected for, so if they were to be regenerated, different dog breeds can be potentially brought back. 

Saving Dogs

Submitted by amprovost on Fri, 03/24/2017 - 15:03

If only one breed of dog could be saved, it would make the most sense to save German Shepherds. These dogs have such a wide range of capablilites, such as being service dogs or being police dogs, making them a useful animal for almost any kind of human. These dogs also have a decent lifespan of 9-13 years, meaning they would be likely to live long enough to reproduce and repopulate the population. These dogs also are known to be one of the most intelligent breeds, and also have a great muscular build, meaning they would be able to pass good genetics on when repopulating the dog population. If the evolution of dogs had to restart at one point, it would make sense for it to start with german shepherds, as these dogs already have some of the most superior genes seen in dogs today.

Preservation of Dog Breeds

Submitted by kmichaud on Fri, 03/24/2017 - 14:59


The breed of dog that should be selected should be one of the most basal breeds which would allow for future domestication and the reintroduction of more derived breeds. Of the basal breeds, we chose to save the Alaskan Malamute which is closely related to Artic wolves. Preservation of the Alaskan Malamute breed would allow for potential differentiation of breeds by artificial selection since the Malamute theoretically contains more ancestral DNA of the most recent common ancestor of the breeds derived from Arctic wolf ancestors. 

Persuasion Writting

Submitted by lcampion on Fri, 03/24/2017 - 14:58

Our beloved dogs are dying out! This is a crisis for dog-lovers everywhere! Not only are dogs wonderful companions, they are also an effective therapy tool and have provide services to people with medical conditions for decades. There is a vaccine that scienctist have created that would allow for one pregnant mother and her pups to survive this horrible viral outbreak! The most obvious choice for this life saving vaccine is a pregnant labrador retriever. This dog bread is simply the best! They can vary in color and provide owners with love and affection! Energectic but able to be trained to be service animals, these dogs have it all! Any other choice would simply be a lacking one when compared to the benefits of having labrador retrievers prevail.

Persuasion Activity -Sophia Hall and Robyn Farrell

Submitted by maurabenson on Fri, 03/24/2017 - 14:52

In the case of this tragic situation, we beliieve that the labrodor should be the breed of dog that should recevie the vaccine. Labradors have very large litters (7.6 dogs per litter) which would allow the population of dogs to regenerate qucikly. Labs are also the number one dog in americam, they are also easy to train. They provide assistance to the handicapped, show competitor, and search and rescue dog, among other canine jobs.


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