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BLAST analysis

Submitted by briangriffin on Mon, 11/13/2017 - 14:43
                There are 2 amino acid differences between Homo sapiens and Pan troglodytes, not including the gaps. There are 8 nucleotides different between the orthologs when not counting the gaps. There are more differences in the nucleotide alignment because a change in the nucleotide sequence does not necesssarily lead to a change in amino acid sequence. But when there is a change in amino acid sequence there is a change in structure and function of that gene, therefore conservation of the amino acid sequence is important. The gaps are in multiples of three and this is because these gaps are deletions or insertions of amino acids which are coded for by a string of three nucleotides.