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Abstract for yeast (perf)

Submitted by daniellam on Fri, 11/17/2017 - 01:54

There are two ADE genes (ADE1 and ADE2) in yeast that must both be functional for them to produce adenine properly. When a haploid with a mutation in ADE1 mates with a haploid with a mutation in ADE2, the two functional halves of the ADE genes complement each other and form a diploid. Complementation can be useful for identifying the ADE mutation of unknown yeast strains. The simplicity of complementation in yeast exemplify a complex mechanism, in which two alleles with different functional parts can complement each other to form an important phenotype. The identification of the unknown mutants came out to be: MA1 is an ADE1 mutant, MA2 is an ADE1 and ADE2 mutant, MB2 and MB4 are ADE2 mutants. These experiments used yeast as a simple model to show the mechanisms of complementation which are complex and an important part of acquiring phenotypes.

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Comments

I think the langauge is clear. In addition, I think your introduction sentence opened the paragraph well and was not too broad. My only advice would be to explain the adenine component a little more clearly.

Good paragraph! One thing I noticed was in your sentence "The simplicity of complementation in yeast exemplify a complex mechanism..." Here, the subject of your sentence is 'the simplicity' which is a singular noun. Therefore, your verb should be 'exemplifies' instead of 'exemplify.'

In the fourth sentences, you can change "examplify" to "examplifies."