There are two ADE genes (ADE1 and ADE2) in yeast that must both be functional for them to produce adenine properly. When a haploid with a mutation in ADE1 mates with a haploid with a mutation in ADE2, the two functional halves of the ADE genes complement each other and form a diploid. Complementation can be useful for identifying the ADE mutation of unknown yeast strains. The simplicity of complementation in yeast exemplify a complex mechanism, in which two alleles with different functional parts can complement each other to form an important phenotype. The identification of the unknown mutants came out to be: MA1 is an ADE1 mutant, MA2 is an ADE1 and ADE2 mutant, MB2 and MB4 are ADE2 mutants. These experiments used yeast as a simple model to show the mechanisms of complementation which are complex and an important part of acquiring phenotypes.
You are here
Each week, post your own Perfect Paragraph and comment on three Perfect Paragraphs. Suggest improvements. Don't just say "Looks good."
- Elevator 1 day 13 hours ago
- PP 1 day 13 hours ago
- Elevator 1 day 14 hours ago
- I think you have some good 2 days 8 hours ago
- Great paragraph! Very 2 days 8 hours ago
- There was a lot of variables 2 days 9 hours ago
- paragraph was clear and the 2 days 9 hours ago
- This paragraph is definatly 2 days 10 hours ago
- Nice paragraph! It sums up 2 days 16 hours ago
- Nice paragraph! I would just 4 days 3 hours ago